Table 3.

Susceptibility pattern of untreated and survived S. aureus cells after consecutive treatment by plasma (disk diffusion assays)

Antibiotics*	Inhibition zone diameter† (mm)											Interpretation criteria‡ (mm)
	Un	T1	T2	T3	T4	T5	T6	T7	T8	T9	T10	S§	I¶	R#
Ampicillin	45	44	45	44	44	44	44	44	43	44	43	≥29	-	≤28
Amoxicillin	46	45	45	44	45	45	44	45	45	44	44	≥29	-	≤28
Cefepime	24	23	23	24	24	24	24	23	23	23	23	≥18	15–17	≤14
Imipenem	49	48	49	48	48	49	48	48	48	45	45	≥16	14–15	≤13
Cephalothin	38	39	38	38	39	38	39	39	37	38	38	≥18	15–17	≤14
Erythromycin	26	26	26	25	26	23	25	26	25	24	25	≥23	14–22	≤13
Amikacin	25	25	23	25	23	23	23	23	24	24	24	≥17	15–16	≤14
Novobiocin††	24	24	24	24	24	24	24	24	24	24	24	-	-	≤16
SXT‡‡	31	32	30	31	30	32	31	30	31	30	30	≥16	11–15	≤10
Ciprofloxacin	33	33	33	31	33	33	33	33	31	32	32	≥21	16–20	≤15
Nitrofurantoin	25	25	24	26	25	25	25	26	25	24	25	≥17	15–16	≤14

^* Disk contents were as follow: 10 μg ampicillin, 10 μg Amoxicillin, 30 μg Cefepime, 10 μg imipenem, 30 μg Cephalothin, 15 μg erythromycin, 30 μg amikacin, 5 μg Novobiocin, 25 μg SXT, 5 μg ciprofloxacin and 300 μg Nitrofurantoin.

^† All inhibition zones are for 6 mm diameter disks except that of Imipenem (10 mm).

^‡ Adopted from CLSI guideline (Jorgensen & Turnidge, 2007).

^§ Sensitive,

^¶ Intermediate,

^# Resistant

^†† Novobiocin resistance is intrinsic to some species such as S. saprophyticus but is uncommon in the other clinically important species such as S. aureus.

^‡‡ Trimethoprim-sulfamethoxazole