Table 3. Binding affinity and Hydrogen bond interaction of Quercetin and Remdesivir with the targets of interest.

Targets	Binding affinity		H-bond interactions
	Quercetin	Remdesivir	Quercetin	Remdesivir
Wnt -3	-8.3	-8	GLU-96, ARG-195, GLU-177	ASN B-191, ASP-174, ARG-195, SER-184, HIS-189, ALA- 185, LEU-259
Frizzel	-6.6	-6.4	ARG-137	GLY-71, TYR-92
Lrp 6	-9.3	-8.4	ILE-1062, ASP-1018, VAL-114, ILE-1105	ASP -799
Spike protein	-6.9	-6.1	SER-591, ASN-536, CYS- 538	GLU-169
ACE2	-8.3	-7.9	LYS-562, GLU-208, GYL-205, ASP-206, LEU-95	GLY A:205, GLN A:98, LYS A:562, GLN A:102, ALA A:396,GLU A:564
TMPRSS2	-7.3	-7.3	VAL-280	SER A:460, GLY A:439, GLY A:462, GLY A:464, SER A:436