Table 1.
Demographic and clinical characteristics of patients with small cell lung cancer in the training set and validation set
| Characteristics | Training set, No. (%) (n = 1465) |
Validation set, No. (%) (n = 844) |
χ 2 | P value |
|---|---|---|---|---|
| Sex | ||||
| Male | 1071 (73.11) | 598 (70.85) | ||
| Female | 394 (26.89) | 246 (29.15) | 1.356 | 0.244 |
| Age | ||||
| ≤ 45 | 110 (7.51) | 41 (4.86) | ||
| 46–60 | 601 (41.02) | 328 (38.86) | ||
| 61–75 | 647 (44.16) | 411 (48.70) | 8.833 | 0.032 |
| > 75 | 107 (7.30) | 64 (7.58) | ||
| Region | ||||
| Eastern | 302 (20.61) | 126 (14.93) | ||
| Southern | 122 (8.33) | 110 (13.03) | ||
| Western | 402 (27.44) | 331 (39.22) | 60.276 | < 0.001 |
| Northern | 639 (43.62) | 277 (32.82) | ||
| Hospital | ||||
| Specialized | 227 (15.49) | 124 (14.69) | ||
| General | 1238 (84.51) | 720 (85.31) | 0.268 | 0.605 |
| Health insurance | ||||
| Urban employees’ basic medical insurance | 388 (26.48) | 138 (16.35) | ||
| Urban residents’ basic medical insurance | 168 (11.47) | 141 (16.71) | ||
| New rural cooperative medical scheme | 833 (56.86) | 506 (59.95) | 61.652 | < 0.001 |
| Self-pay | 56 (3.82) | 20 (2.37) | ||
| Other | 20 (1.37) | 39 (4.62) | ||
| Smoke | ||||
| No | 582 (39.73) | 348 (41.23) | ||
| Yes | 883 (60.27) | 496 (58.77) | 0.504 | 0.478 |
| Alcohol use | ||||
| No | 977 (66.69) | 555 (65.76) | ||
| Yes | 488 (33.31) | 289 (34.24) | 0.208 | 0.648 |
| TNM Stage | ||||
| I | 75 (5.12) | 47 (5.57) | ||
| II | 141 (9.62) | 77 (9.12) | ||
| III | 592 (40.41) | 331 (39.22) | 0.720 | 0.868 |
| IV | 657 (44.85) | 389 (46.09) | ||
| Surgery | ||||
| No | 1373 (93.72) | 800 (94.79) | ||
| Yes | 92 (6.28) | 44 (5.21) | 1.099 | 0.294 |
| Chemotherapy | ||||
| No | 305 (20.82) | 216 (25.59) | ||
| Yes | 1160 (79.18) | 628 (74.41) | 6.983 | 0.008 |
| Radiotherapy | ||||
| No | 1095 (74.74) | 670 (79.38) | ||
| Yes | 370 (25.26) | 174 (20.62) | 6.401 | 0.011 |
Notes: Eastern, Southern, Western, and Northern represent respectively Eastern of Shandong, Southern of Shandong, Western of Shandong, and Northern of Shandong; Specialized, General represent respectively specialized tumor hospitals and general hospitals