Table 3.
NRI and IDI of the nomogram and the TNM stage in survival prediction for SCLC patients in the training and validation sets
| Index | Training set | Validation set | |||||
|---|---|---|---|---|---|---|---|
| Estimate | 95%CI | p | Estimate | 95%CI | p | ||
| NRI (vs. the TNM stage) | |||||||
| 1-year OS | 0.255 | 0.189–0.308 | < 0.001 | 0.154 | 0.034–0.257 | 0.012 | |
| 3-year OS | 0.210 | 0.143–0.274 | < 0.001 | 0.157 | -0.030-0.271 | 0.096 | |
| 5-year OS | 0.198 | 0.106–0.274 | < 0.001 | -0.040 | -0.226-0.106 | 0.363 | |
| IDI (vs. the TNM stage) | |||||||
| 1-year OS | 0.056 | 0.040–0.080 | < 0.001 | 0.040 | 0.014–0.065 | 0.004 | |
| 3-year OS | 0.047 | 0.032–0.071 | < 0.001 | 0.025 | -0.010-0.052 | 0.112 | |
| 5-year OS | 0.041 | 0.024–0.067 | < 0.001 | -0.006 | -0.064-0.031 | 0.715 | |
Note: NRI, Net Reclassification Improvement; IDI, Integrated Discrimination Improvement; OS, overall survival