Table 2.

Questionnaires and neuropsychological test battery included in the ICANSLEEP-1 study with their outcome measures

Domains	Assessment tests	Outcome measures	Range	Evaluated time frame
Sleep Questionnaires
Insomnia	ISI	Total Score	0–28 (> 7)	Over the last two weeks
Sleep Quality	PSQI	Total score	0–21	Over the last month
Circadian Typology	MEQ	Total score	16–86	-
Quality of Life Questionnaires
Cognitive complaint	Fact-Cog	PCI	0–72	Over the last seven days
		PCA	0–28
		QoL	0–16
		Oth	0–16
Quality of life	FACT-G (patients)	Total score	0–108	Over the last seven days
Pain	BPI	Severity of pain	0–10	Over the last eight days
		Interference of pain	0–10
Fatigue	FACIT-F (patients)	Total score	0–52	Over the last seven days
	MFI-20	General and physical fatigue	9–45	-
		Reduced activity	3–15
		Reduced motivation	2–10
		Mental fatigue	6–30
Anxiety	STAI-Y	State score	20–80	At the time being
		Trait score	20–80	Generally speaking,
Depression	BDI-II	Total score	0–63	Over the last two weeks
Neuropsychological tests
Global functioning	MoCA	Total Score	0–30
Episodic Memory	HVLT	Total free recall score	0–36
		Delayed recall score	0–12
Working Memory	WMS-III subset of spatial memory	Total number of correct trials forward	0–16
		Total number of correct trials backward	0–16
	Baddeley dual Task	Digit span: number of correct sequences	3–10
		Motor Task: number of boxes checked in 2 min	0–332
		Dual task: number of correct sequences; number of boxes checked	0–332
Attention	D2-R	Number of target characters processed	0–513
		E %: [(EO + EC)/PTO] x100	0–100
Executive Functions	N-Back	Number of correct responses	0–48
	TMT (A – B)	Time in seconds of part A	≥ 0s
		Time in seconds part B – A	≥ 0s
	Stroop	Naming	≥ 0s
		Reading	≥ 0s
		Interference Time	≥ 0s
	Verbal Fluency	Letters P & R

ISI: Insomnia Severity Index, PSQI: Pittsburgh Sleep quality Index, MEQ: Morningness-Eveningness Questionnaire, FACT-COG: Functional Assessment of Cancer Therapy – Cognitive Function, PCI: Perceived Cognitive Impairment, PCA: Perceived Cognitive Abilities, QOL: impact on Quality of Life, Oth: Comments from Others, FACT-G: The Functional Assessment of Cancer Therapy – General, BPI: Brief Pain Inventory, FACIT-F: Functional Assessment of Chronic Illness Therapy – Fatigue, MFI-20: Multidimensional Fatigue Inventory, STAI-Y: State-Trait Anxiety Inventory, BDI-II: Beck’s Depression Inventory-2nd edition, MoCA: Montreal Cognitive Assessment; HVLT: Hopkins Verbal Learning Test; WMS-III: Wechsler Memory Scale – 3rd edition, D2-R: d2 Test of Attention-Revised, E%: percent of Errors, EO: Errors of Omission, EC: Errors of Commission, PTO: Processed Target Objects, TMT: Trail Making Test