Table 7.

The SNPs of CYP4B1 associated with susceptibility of breast cancer in patients (Reproductive number)

SNP ID	Model	Genotype	Case	Control	OR (95% CI)	p
			= 1	> 1
rs2297813	Allele	G	349 (82.7%)	423 (88.1%)	1.00	0.021*
		T	73 (17.3%)	57 (11.9%)	1.55 (1.07–2.26)
	Codominant	G/G	142 (67.3%)	185 (77.1%)	1.00	0.080
		G/T	65 (30.8%)	53 (22.1%)	1.57 (1.02–2.43)
		T/T	4 (1.9%)	2 (0.8%)	2.55 (0.44–14.66)
	Dominant	G/G	142 (67.3%)	185 (77.1%)	1.00	0.029*
		G/T-T/T	69 (32.7%)	55 (22.9%)	1.61 (1.05–2.47)
	Recessive	G/G-G/T	207 (98.1%)	238 (99.2%)	1.00	0.340
		T/T	4 (1.9%)	2 (0.8%)	2.28 (0.40-13.03)
	Over-dominant	G/G-T/T	146 (69.2%)	187 (77.9%)	1.00	0.049*
		G/T	65 (30.8%)	53 (22.1%)	1.55 (1.00-2.39)
	Log-additive				1.58 (1.06–2.35)	0.024*
rs12142787	Allele	G	300 (71.8%)	372 (77.8%)	1.00	0.037*
		A	118 (28.2%)	106 (22.2%)	1.38 (1.02–1.87)
	Codominant	G/G	106 (50.7%)	147 (61.5%)	1.00	0.100
		A/G	88 (42.1%)	78 (32.6%)	1.51 (1.01–2.28)
		A/A	15 (7.2%)	14 (5.9%)	1.59 (0.72–3.53)
	Dominant	G/G	106 (50.7%)	147 (61.5%)	1.00	0.033*
		A/G-A/A	103 (49.3%)	92 (38.5%)	1.53 (1.03–2.25)
	Recessive	G/G-A/G	194 (92.8%)	225 (94.1%)	1.00	0.450
		A/A	15 (7.2%)	14 (5.9%)	1.35 (0.62–2.94)
	Over-dominant	G/G-A/A	121 (57.9%)	161 (67.4%)	1.00	0.071
		A/G	88 (42.1%)	78 (32.6%)	1.44 (0.97–2.15)
	Log-additive				1.38 (1.01–1.89)	0.044*
rs3766197	Allele	C	356 (84.4%)	394 (82.1%)	1.00	0.362
		T	66 (15.6%)	86 (17.9%)	0.85 (0.60–1.21)
	Codominant	C/C	150 (71.1%)	165 (68.8%)	1.00	0.220
		T/C	56 (26.5%)	64 (26.7%)	0.90 (0.58–1.38)
		T/T	5 (2.4%)	11 (4.6%)	0.39 (0.13–1.19)
	Dominant	C/C	150 (71.1%)	165 (68.8%)	1.00	0.350
		T/C-T/T	61 (28.9%)	75 (31.2%)	0.82 (0.54–1.24)
	Recessive	C/C-T/C	206 (97.6%)	229 (95.4%)	1.00	0.096
		T/T	5 (2.4%)	11 (4.6%)	0.41 (0.13–1.22)
	Over-dominant	C/C-T/T	155 (73.5%)	176 (73.3%)	1.00	0.770
		T/C	56 (26.5%)	64 (26.7%)	0.94 (0.61–1.44)
	Log-additive				0.78 (0.55–1.12)	0.170

95% CI: 95% confidence interval; OR: Odds ratio

p < 0.05: Bold text and ‘*’ represent statistical significance