FIGURE 7.
Building advanced human organoids by integrating novel strategies and technologies. (A) A human‐airway‐on‐a‐chip for studying viral infection. Reproduced with permission. 146 Copyright 2021, Springer Nature. (B) SARS‐CoV‐2 infection in brain organoids with innately developing microglia. Reproduced with permission. 147 Copyright 2022, Springer Nature. (C,D) Pericyte‐like cell‐containing cortical organoids were generated by the integration of pericyte‐like cells into cortical brain organoids and were prone to be infected by SARS‐CoV‐2. Reproduced with permission. 148 Copyright 2021, Springer Nature. (E,F) SARS‐CoV‐2 induced intestinal responses with a biomimetic human gut‐on‐chip. Reproduced with permission. 149 Copyright 2021, Science China Press. (G) The human multi‐organ‐on‐a‐chip concept. Reproduced with permission. 150 Copyright 2011, Elsevier. (H). Generation multisensor‐integrated organs‐on‐chips platform. Reproduced with permission. 151 Copyright 2017, National Academy of Sciences. (I,J). Single‐cell RNA‐seq analysis of hPSC‐derived airway organoids. Reproduced with permission. 60 Copyright 2021, Elsevier.