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. 2023 Nov 28;16:5613–5628. doi: 10.2147/JIR.S419186

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© 2023 Lou et al.

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Effects of ATF3 knockdown on extracellular matrix proteins in the articular cartilage of rats with OA. (A–D), Expression of collagen II (A), aggrecan (B) and MMP-13 (C) in rat knee joints from rats (n=4) detected by immunohistochemistry and quantified by ImageJ software (D). Scale bar = 400 μm. Error bars are mean ± s.d. **P < 0.01 vs OA+si-NC group.