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. 2023 Nov 28;18:2739–2754. doi: 10.2147/COPD.S428984

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© 2023 Jiang et al.

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Identification of DeLMRGs in COPD patients. (A) Volcano plot of COPD-related DEGs, graphed with log2FoldChange on the abscissa and -log10 on the ordinate (adjusted P value): Nodes in red represent DEGs up-regulated, nodes in blue represent DEGs down-regulated, and nodes in gray represent genes not significantly differentially expressed. (B) Heat map of top 20 COPD-related DEGs: disease samples are indicated by group1, normal control samples by group2, and high gene expression is indicated by red with low gene expression by blue; (C) Venn diagram of DeLMRGs derived from DEGs and LMRGs intersection: green represents LMRGs, blue represents upregulated DEGs and pink represents downregulated DEGs.

Abbreviations: DEGs, differentially expressed genes; LMRGs, lipid metabolism-related genes; DeLMRGs, differentially expressed lipid metabolism-related genes.