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. 2023 Dec 2;15(12):e49835. doi: 10.7759/cureus.49835

Table 6. Causes of hypermagnesemia.

Note: Table 6 was developed on the basis of earlier published paper [27].

Causes Description
Increased intake    Amplified absorption due to poor gut motility (typical in the elderly, treatment with anticholinergics or opioids, inflammatory bowel disease patients).
Laxatives (Mg2+ citrate), antacids (Mg2+ trisilicate), bowel preparation agents (Na+ picosulfate/Mg2+ citrate), and in treatment for eclampsia (intravenous Mg2+ sulfate).
Extreme oral intake in chronic kidney disease patients.
Milk-alkali syndrome (large amounts of Ca2+ and Mg2+).
Newborns to mothers receiving Mg2+ sulfate for eclampsia.
Decreased renal excretion    Acute or chronic kidney disease.
Adrenocortical insufficiency
Hyperparathyroidism
Hypercalcemia and/or hypocalciuria e.g., Familial hypocalciuric hypercalcemia (FHH).
Lithium-based psychotropic drugs.
Compartment shift or leak    Hemolysis.
Tumor lysis syndrome.
Rhabdomyolysis.
Acidosis, such as in diabetic ketoacidosis.