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. 2023 Nov 16;15:1269952. doi: 10.3389/fnagi.2023.1269952
3Rs Reduction, Replacement, Refinement
AChE Acetylcholinesterase
AD Alzheimer’s disease
AMPK Adenosine 5‘-monophosphate (AMP)-activated protein kinase
APP/PS1 (APPswe,PSEN1dE9); APP: Amyloid precursor protein
Amyloid-β
BACE1 Beta-site amyloid precursor protein cleaving enzyme 1
BchE Butyrylcholinesterase
CAT Catalase from Micrococcus Lysodeikticus
CNS Central nervous system
CON Control group
DD H2O Double distilled water
EX Exercise
EX+GCA Exercise+ Chlorogenic acid
FDA U.S. Food and Drug Administration
GAPDH Glyceraldehyde -3-phosphate dehydrogenase
GCA Chlorogenic acid
GSH-PX Glutathione peroxidase
H2O2 Hydrogen peroxide
HE Hematoxylin-eosin staining
IL-10 Interleukin-10
IL-1β Interleukin-1β
IL-6 Interleukin-6
LC3 MAP1LC3
MAP2 (Microtubule-associated protein) 2
MDA Malondialdehyde
NeuN Neuronal nuclei antigen (NeuN /RBFOX3)
OD Optical density
PBS Phosphate buffered saline
PGC-1α Peroxisome proliferators-activated receptor γ coactivator l alpha
PPARγ Peroxisome proliferator activated receptor γ
ROS Reactive oxygen species
SIRT1 Silent Information Regulator 1
SOD Superoxide dismutase
TNF-α Tumor necrosis factor-α
WB Western blot