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. 2023 Nov 17;13:1249172. doi: 10.3389/fonc.2023.1249172

Table 2.

Marker: analyzable TMAs (n), mean of marker expression between 0 (negative) and 1 (positive), p value and hazard ratio of univariate Cox regression of the marker and overall survival.

Marker N mean p hazard ratio
AKR1 448 0.91 0.09 0.72
ARID1A 806 0.9 0.73 0.96
BRG1 680 0.97 0.97 0.77
BRM 693 0.9 0.23 1.25
Carbonic anhydrase IX 330 0.5 0.13 0.81
CD3 cell tumor infiltration 775 0.35 0.00003 0.64
CD34 331 0.4 0.12 0.8
CD36 389 0.42 0.001 0.66
CD66b 587 0.48 0.79 0.97
CDKN2A/p16 416 0.3 0.023 1.16
Claudin-18 440 0.18 0.56 1.1
c-Myc 463 0.18 0.47 1.11
Cyclin D1 549 0.57 0.98 0.988
E-Cadherin 331 0.96 0.55 0.82
FBP1 525 0.82 0.006 0.67
FBXW7 511 0.93 0.38 0.82
GATA-6 450 0.11 0.21 0.78
Grem1 291 0.9 0.54 0.87
H3K27m3 382 0.87 0.42 0.86
Her2 766 0.08 0.007 0.57
HMGB1 499 0.77 0.13 0.82
IMP3 330 0.76 0.007 1.59
ini1 498 1.0 0.16 0.24
Integrin alpha-5 568 0.15 0.14 1.22
Integrin beta-1 581 0.2 0.02 1.36
Integrin beta-4 400 0.79 0.008 0.67
Ki67 389 0.54 0.76 1.04
KRas 477 0.19 0.08 1.29
Lag3 398 0.36 0.14 0.82
Mdm2 386 0.05 0.82 1.07
Mesothelin 429 0.38 0.18 1.19
MET 447 0.09 0.63 1.11
MHC-1 388 0.96 0.84 1.06
Mlh1 807 0.96 0.57 1.3
NOPE-Ca 333 0.08 0.25 1.31
p53 775 0.8 0.75 0.96
PD-L1 451 0.14 0.56 0.9
PIK3CA 416 0.06 0.82 1.06
PTEN 564 0.92 0.03 0.66
TIM3 448 0.54 0.7 0.95
TROP-2 546 0.89 0.97 1.0
UBQLN4 418 0.77 0.98 1.0
XIAP 335 0.91 0.55 1.17
preserved Y chromosome 681 0.41 0.001 0.68