Table 2.
Marker: analyzable TMAs (n), mean of marker expression between 0 (negative) and 1 (positive), p value and hazard ratio of univariate Cox regression of the marker and overall survival.
| Marker | N | mean | p | hazard ratio |
|---|---|---|---|---|
| AKR1 | 448 | 0.91 | 0.09 | 0.72 |
| ARID1A | 806 | 0.9 | 0.73 | 0.96 |
| BRG1 | 680 | 0.97 | 0.97 | 0.77 |
| BRM | 693 | 0.9 | 0.23 | 1.25 |
| Carbonic anhydrase IX | 330 | 0.5 | 0.13 | 0.81 |
| CD3 cell tumor infiltration | 775 | 0.35 | 0.00003 | 0.64 |
| CD34 | 331 | 0.4 | 0.12 | 0.8 |
| CD36 | 389 | 0.42 | 0.001 | 0.66 |
| CD66b | 587 | 0.48 | 0.79 | 0.97 |
| CDKN2A/p16 | 416 | 0.3 | 0.023 | 1.16 |
| Claudin-18 | 440 | 0.18 | 0.56 | 1.1 |
| c-Myc | 463 | 0.18 | 0.47 | 1.11 |
| Cyclin D1 | 549 | 0.57 | 0.98 | 0.988 |
| E-Cadherin | 331 | 0.96 | 0.55 | 0.82 |
| FBP1 | 525 | 0.82 | 0.006 | 0.67 |
| FBXW7 | 511 | 0.93 | 0.38 | 0.82 |
| GATA-6 | 450 | 0.11 | 0.21 | 0.78 |
| Grem1 | 291 | 0.9 | 0.54 | 0.87 |
| H3K27m3 | 382 | 0.87 | 0.42 | 0.86 |
| Her2 | 766 | 0.08 | 0.007 | 0.57 |
| HMGB1 | 499 | 0.77 | 0.13 | 0.82 |
| IMP3 | 330 | 0.76 | 0.007 | 1.59 |
| ini1 | 498 | 1.0 | 0.16 | 0.24 |
| Integrin alpha-5 | 568 | 0.15 | 0.14 | 1.22 |
| Integrin beta-1 | 581 | 0.2 | 0.02 | 1.36 |
| Integrin beta-4 | 400 | 0.79 | 0.008 | 0.67 |
| Ki67 | 389 | 0.54 | 0.76 | 1.04 |
| KRas | 477 | 0.19 | 0.08 | 1.29 |
| Lag3 | 398 | 0.36 | 0.14 | 0.82 |
| Mdm2 | 386 | 0.05 | 0.82 | 1.07 |
| Mesothelin | 429 | 0.38 | 0.18 | 1.19 |
| MET | 447 | 0.09 | 0.63 | 1.11 |
| MHC-1 | 388 | 0.96 | 0.84 | 1.06 |
| Mlh1 | 807 | 0.96 | 0.57 | 1.3 |
| NOPE-Ca | 333 | 0.08 | 0.25 | 1.31 |
| p53 | 775 | 0.8 | 0.75 | 0.96 |
| PD-L1 | 451 | 0.14 | 0.56 | 0.9 |
| PIK3CA | 416 | 0.06 | 0.82 | 1.06 |
| PTEN | 564 | 0.92 | 0.03 | 0.66 |
| TIM3 | 448 | 0.54 | 0.7 | 0.95 |
| TROP-2 | 546 | 0.89 | 0.97 | 1.0 |
| UBQLN4 | 418 | 0.77 | 0.98 | 1.0 |
| XIAP | 335 | 0.91 | 0.55 | 1.17 |
| preserved Y chromosome | 681 | 0.41 | 0.001 | 0.68 |