Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
G6PDH role in immune responses. G6PDH enzymatic activity may increase NADPH levels and thus interfere with intracellular redox balance. Reactive oxygen species (ROS) can interfere with pathogen replication, suggesting an indirect role for G6PDH in the host’s immune response. ROS can inhibit replication in certain pathogens (e.g., bacteria and fungi), or induce parasite replication.
