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. 2023 Nov 16;14:1259350. doi: 10.3389/fendo.2023.1259350

Table 1.

Characteristics of the study participants.

  Men Women
n=254 n=218 p-value
Age, years 62.4 ±10.2 62.1 ±10.4 0.760
Body height, cm 166.2 ±6.4 154.1 ±5.9 <0.001
Body weight, kg 64.2 ±8.6 53.4 ±9.7 <0.001
BMI, kg/m2 23.2 ±2.6 22.5 ±3.6 0.007
Medical history
Stroke, n (%) 5 (2.0) 8 (3.7) 0.276
Heart disease, n (%) 21 (8.3) 6 (2.8) 0.010
Diabetes, n (%) 26 (10.2) 13 (6.0) 0.097
Hypertension, n (%) 93 (36.6) 60 (27.5) 0.039
Dyslipidemia, n (%) 50 (19.7) 57 (26.1) 0.099
Smoker, n (%) 54 (21.3) 7 (3.2) <0.001
Vitamin D administration, n (%) 2 (0.8) 7 (3.2) 0.088
Sarcopenia diagnosis
Muscle mass loss (%) 68 (26.8) 39 (18.1) 0.027
Muscle function loss (%) 25 (9.8) 31 (14.4) 0.154
Sarcopenia (%) 14 (5.5) 11 (5.1) 1.000
Quantity
CSA, cm2 58.0 ±9.5 42.3 ±7.4 <0.001
CSA / height, cm 0.349 ±0.054 0.274 ±0.044 <0.001
CSA / height2, % 0.210 ±0.033 0.178 ±0.027 <0.001
CSA / weight, cm2/kg 0.907 ±0.117 0.800 ±0.119 <0.001
CSA / BMI, 104·cm4/kg 2.51 ±0.36 1.90 ±0.32 <0.001
ASM, kg 20.8 ±2.8 14.4 ±2.3 <0.001
SMI, kg / m2 7.53 ±0.77 6.06 ±0.76 <0.001
ASM / weight, % 32.5 ±2.3 27.2 ±2.4 <0.001
ASM / BMI, m2 0.90 ±0.10 0.65 ±0.08 <0.001
Quality
CTV, HU 54.3 ±3.4 50.6 ±4.1 <0.001
CTV / BMI, HU·m2/kg 2.37 ±0.34 2.31 ±0.41 0.075
KES / CSA, N/cm2 7.81 ±1.40 6.96 ±1.32 <0.001
Quality×Quantity
CSA × CTV, cm2·HU 3157 ±595 2146 ±444 <0.001
CSA × CTV / height, cm·HU 19.0 ±3.4 13.9 ±2.7 <0.001
CSA × CTV / height2, HU 0.114 ±0.020 0.090 ±0.017 <0.001
CSA × CTV / weight, cm2·HU/kg 49.4 ±8.2 40.7 ±8.0 <0.001
CSA × CTV / BMI, 104·cm4·HU/kg 137 ±25 97 ±21 <0.001
Physical performance
Grip, kg 37.6 ±6.5 23.3 ±4.5 <0.001
KES, N 453 ±108 294 ±76 <0.001
Leg Power, W 535 ±156 321 ±93 <0.001
Sit up, times 13.4 ±5.0 8.0 ±5.5 <0.001
Walking, m/seconds 1.41 ±0.18 1.38 ±0.16 0.032
Fast walking, m/seconds 1.92 ±0.24 1.80 ±0.20 <0.001
Balance, seconds 16.1 ±24.0 13.9 ±19.5 0.292
Reaction, seconds 0.43 ±0.08 0.46 ±0.07 <0.001

Values are expressed as numbers (%).

Means are expressed ± standard deviation.

p-values were obtained from the t-test for continuous data and the χ2 test and fisher's exact test for categorical data.

Abbreviations: BMI, body mass index; CSA, cross-sectional area; ASM, appendicular skeletal muscle mass; SMI, skeletal muscle mass index; CTV, computed tomography attenuation value; HU, Hounsfield unit; KES, knee extension strength.