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. 2023 Nov 17;14:1290952. doi: 10.3389/fmicb.2023.1290952

Table 1.

Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of CSA-13, CSA-131, and LL-37 against Staphylococcus aureus Xen29, and Pseudomonas aeruginosa ATCC 27853 and DSM 19880, and two clinical isolates – P. aeruginosa 4B and Ochrobactrum spp. 10B in the presence of NaCl concentration (0–300 mM).

Compound NaCl [mM] MIC/MBC [μg/mL]
Staphylococcus aureus Xen29 Pseudomonas aeruginosa ATCC 27853 Pseudomonas aeruginosa PAO1 DSM 19880 Pseudomonas aeruginosa 4B Ochrobactrum spp. 10B
CSA-13 0 0.5/0.5 2/4 2/2 1/2 1/2
20 0.5/0.5 2/4 2/2 1/2 1/2
60 0.5/0.5 2/4 2/4 1/2 1/2
100 0.5/0.5 2/4 2/4 1/2 1/2
150 0.5/0.5 2/4 2/4 1/2 1/2
300 0.5/0.5 2/4 2/4 1/4 1/4
CSA-131 0 0.5/1 2/4 1/1 2/2 0.5/1
20 0.5/1 2/4 1/1 2/4 0.5/1
60 0.5/1 2/4 1/1 2/2 0.5/1
100 0.5/0.5 2/4 1/2 2/2 0.5/1
150 0.5/0.5 2/4 1/1 2/4 0.5/0.5
300 0.5/0.5 2/4 1/1 2/4 0.5/1
LL-37 0 >256/>256 128/128 16/32 128/128 8/16
20 -* - 16/64 - 8/32
60 - - 16/64 - 8/32
100 - - 32/64 - 16/32
150 - - 64/128 - 16/64
300 - - 128/>256 - 64/>256

* - not determined.