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. 2023 Nov 1;15(11):e48120. doi: 10.7759/cureus.48120

Table 2. The relationship between urothelial cancer and PD-1(rs2227981) and PD-L1(rs2890658) polymorphisms.

Adjusted by age, gender, and smoking status

 *:P<0.05, OR - Odd Ratio 

  Case(n=256) Control(n=211) Crude OR(95%CI) Adjusted OR(95%CI)
PD1 C/C 134 130 ref ref
C/T 104 68 1.48(1.01-2.19)* 1.55(1.02-2.35)*
T/T 18 13 1.34(0.63-2.85) 1.15(0.52-2.56)
C/T+T/T 122 81 1.46(1.01-2.12)* 1.48(1.00-2.19)
PDL1 A/A 218 187 ref ref
A/C 36 22 1.41(0.80-2.48) 1.42(0.78-2.60
C/C 2 1 1.72(0.16-19.17) 1.21(0.11-13.81)
A/C+C/C 38 23 1.42(0.82-2.48) 1.42(0.79-2.54)