Table 2. The relationship between urothelial cancer and PD-1(rs2227981) and PD-L1(rs2890658) polymorphisms.
Adjusted by age, gender, and smoking status
*:P<0.05, OR - Odd Ratio
| Case(n=256) | Control(n=211) | Crude OR(95%CI) | Adjusted OR(95%CI) | ||
| PD1 | C/C | 134 | 130 | ref | ref |
| C/T | 104 | 68 | 1.48(1.01-2.19)* | 1.55(1.02-2.35)* | |
| T/T | 18 | 13 | 1.34(0.63-2.85) | 1.15(0.52-2.56) | |
| C/T+T/T | 122 | 81 | 1.46(1.01-2.12)* | 1.48(1.00-2.19) | |
| PDL1 | A/A | 218 | 187 | ref | ref |
| A/C | 36 | 22 | 1.41(0.80-2.48) | 1.42(0.78-2.60 | |
| C/C | 2 | 1 | 1.72(0.16-19.17) | 1.21(0.11-13.81) | |
| A/C+C/C | 38 | 23 | 1.42(0.82-2.48) | 1.42(0.79-2.54) | |