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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: J Alzheimers Dis. 2023;92(3):975–987. doi: 10.3233/JAD-221151

Table 3.

Regression analyses examining the association between cognitive performance assessment scores andvigorous-intensity physical activity (n = 2,377)

β (95% CI)

Model Unadjusted Minimally adjusted Fully adjusted
CERAD.IR
 VPA<1 h Ref Ref Ref

 VPA 1–3 h 1.58 (0.86, 2.31)*** 0.56(−0.12, 1.23)^ 0.41 (−0.26, 1.08)
 VPA 3–6 h 1.26(0.39,2.14)** 0.55 (−0.26, 1.36) 0.42 (−0.39, 1.23)
 VPA 6 + h 0.69 (−0.06, 1.45)^ 0.42 (−0.27, 1.12) 0.30 (−0.40, 0.99)
 R-squared 0.01 0.188 0.197

Partial Eta-squared VPA 0.011 VPA 0.002 VPA 0.001
Gender 0.041 Gender 0.033
Age 0.068 Age 0.044
Race 0.009 Race 0.007
Education 0.066 Education 0.056
BMI 0.001
Handgrip 0.004

CERAD.DR
 VPA< 1 h Ref Ref Ref

 VPA 1–3 h 0.84 (0.48, 1.20)*** 0.37 (0.03, 0.71)* 0.33 (−0.01, 0.67)^
 VPA 3–6 h 0.60 (0.16, 1.04)** 0.28 (−0.13, 0.69) 0.23 (−0.18, 0.64)
 VPA 6 + h 0.24 (−0.13, 0.62) 0.07 (−0.28, 0.42) 0.04 (−0.31, 0.39)
 R-squared 0.01 0.172 0.18

Partial Eta-squared VPA 0.011 VPA 0.003 VPA 0.002
Gender 0.036 Gender 0.025
Age 0.079 Age 0.051
Race 0.013 Race 0.014
Education 0.039 Education 0.034
BMI 0.005
Handgrip 0.002

AFT
 VPA< 1 h Ref Ref Ref

 VPA 1–3 h 2.69 (1.82, 3.56)*** 1.01 (0.21, 1.82)* 0.76 (−0.04, 1.56)^
 VPA 3–6 h 3.23 (2.18, 4.28)*** 1.57 (0.60, 2.53)** 1.27 (0.31, 2.24)**
 VPA 6 + h 1.86(0.96, 2.77)*** 1.03 (0.20, 1.86)* 0.83 (0.00, 1.66)^
 R-squared 0.031 0.208 0.226

Partial Eta-squared VPA 0.032 VPA 0.008 VPA 0.005
Age 0.067 Age 0.043
Race 0.070 Race 0.069
Education 0.074 Education 0.061
BMI 0.003
Handgrip 0.007

DSS
 VPA< 1 h Ref Ref Ref

 VPA 1–3 h 9.43(6.73,12.13)*** 2.75 (0.72, 4.78)** 1.81 (−0.18, 3.80)^
 VPA 3–6 h 9.48(6.22,12.74)*** 3.68 (1.22, 6.13)** 2.81 (0.41, 5.22)*
 VPA 6 + h 4.28 (1.47, 7.09)** 2.03 (−0.07, 4.13)^ 1.16 (−0.90, 3.22)
 R-squared 0.031 0.473 0.499

Partial Eta-squared VPA 0.033 VPA 0.007 VPA 0.003
Gender 0.047 Gender 0.055
Age 0.129 Age 0.113
Race 0.116 Race 0.120
Education 0.246 Education 0.224
BMI 0.001
Handgrip 0.015

Minimally adjusted model included the covariates age, gender, race, and education Fully adjusted model included the covariates age, gender, race, education, marital status, BMI, handgrip strength, hypertension status, diabetes status, depression status, comorbid score, and serum HDL level.

***

p<0.001,

**

p<0.01,

*

p<0.05.

^

p<0.1 Ref, reference category; CERAD.IR, immediate recall memory test; CERAD.DR, delayed recall memory test; AFT, animal fluency test; DSS, digit symbol substitution test. Effect size is represented by Partial Eta-squared.