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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: J Alzheimers Dis. 2023;92(3):975–987. doi: 10.3233/JAD-221151

Table 5.

Regression analyses examining the association between cognitive performance assessment scores and moderate-intensity physical activity (n = 2,377)

β (95% CI)

Model Unadjusted Minimally adjusted Fully adjusted
CERAD.IR
MPA No activity Ref Ref Ref
MPA<1h 0.14 (−0.66, 0.94) −0.07 (−0.80, 0.66) −0.12 (−0.85, 0.60)
MPA 1–3 h 0.71 (0.19, 1.23)** 0.34 (−0.13, 0.81) 0.23 (−0.25, 0.70)
MPA 3–6 h 0.53 (−0.03, 1.08)^ 0.06 (−0.44, 0.57) −0.06 (−0.57, 0.45)
MPA 6–9 h 0.76(0.01, 1.52)* 0.37 (−0.32, 1.05) 0.22 (−0.47, 0.90)
MPA 9–12 h 0.49 (−0.38, 1.36) 0.09 (−0.70, 0.88) −0.06 (−0.85, 0.73)
MPA 12 + h 0.61 (0.00, 1.21)* 0.25 (−0.30, 0.80) 0.04 (−0.51, 0.60)
R-squared 0.002 0.187 0.196

Partial Eta-squared MPA 0.005 MPA 0.001 MPA 0.001
Gender 0.039 Gender 0.032
Age 0.072 Age 0.046
Race 0.010 Race 0.007
Education 0.068 Education 0.058
Handgrip 0.004
CERAD.DR

MPA No activity Ref Ref Ref
MPA< 1 h 0.34 (−0.06, 0.74)^ 0.28 (−0.08, 0.65) 0.25 (−0.11, 0.62)
MPA 1–3 h 0.40(0.15,0.66)** 0.23 (−0.01, 0.46)* 0.20 (−0.04, 0.44)
MPA 3–6 h 0.27 (0.00, 0.55)^ 0.06 (−0.19, 0.31) 0.05 (−0.21, 0.30)
MPA 6–9 h 0.55 (0.18,0.93)** 0.34 (0.00, 0.68)* 0.31 (−0.04, 0.66)
MPA 9–12 h 0.25 (−0.18,0.69) 0.03 (−0.37, 0.43) 0.00 (−0.40, 0.40)
MPA 12 + h 0.33 (0.03, 0.63)* 0.15 (−0.12, 0.43) 0.10 (−0.18, 0.38)
R-squared 0.004 0.171 0.180

Partial Eta-squared MPA 0.007 MPA 0.003 MPA 0.003
Gender 0.036 Gender 0.023
Age 0.083 Age 0.054
Race 0.013 Race 0.014
Education 0.041 Education 0.034
BMI 0.005
Handgrip 0.003

AFT
MPA No activity Ref Ref Ref
MPA< 1 h 0.70 (−0.026, 1.66) 0.33 (−0.54, 1.19) 0.26 (−0.60, 1.12)
MPA 1–3 h 1.52(0.90, 2.14)*** 1.05 (0.49, 1.60)*** 0.90 (0.34, 1.46)**
MPA 3–6 h 1.56(0.90, 2.22)*** 0.95 (0.35, 1.55)** 0.79(0.18, 1.39)*
MPA 6–9 h 1.38 (0.48,2.29)** 0.83 (0.02, 1.64)* 0.61 (−0.20, 1.43)
MPA 9–12 h 1.29 (0.25, 2.33)* 0.78 (−0.17, 1.72)^ 0.62 (−0.32, 1.55)
MPA 12 + h 2.52(1.80, 3.24)*** 1.66(1.01,2.32)*** 1.39(0.73,2.05)***
R-squared 0.023 0.212 0.228

Partial Eta-squared MPA 0.025 MPA 0.013 MPA 0.009
Age 0.071 Age 0.046
Race 0.072 Race 0.071
Education 0.076 Education 0.063
BMI 0.004
Handgrip 0.007

DSS
MPA No activity Ref Ref Ref
MPA< 1 h 5.02 (2.03, 8.01)** 3.57 (1.37, 5.76)** 3.36(1.22, 5.50)**
MPA 1–3 h 5.27 (3.34, 7.19)*** 2.82 (1.40, 4.23)*** 2.06 (0.67, 3.45)**
MPA 3–6 h 5.46 (3.40, 7.52)*** 2.23 (0.71, 3.75)** 1.38 (−0.13, 2.88)^
MPA 6–9 h 4.73 (1.92, 7.53)*** 1.82 (−0.24, 3.88)^ 0.74 (−1.29, 2.77)
MPA 9–12 h 5.35 (2.11, 8.59)** 2.67 (0.29, 5.06)* 1.83 (−0.51, 4.16)
MPA 12 + h 4.01 (1.78, 6.25)*** 1.38 (−0.28, 3.04)^ 0.13 (−1.51, 1.77)
R-squared 0.018 0.474 0.501

Partial Eta-squared MPA 0.021 MPA 0.009 MPA 0.007
Gender 0.044 Gender 0.053
Age 0.173 Age 0.119
Race 0.120 Race 0.124
Education 0.247 Education 0.225
BMI 0.001
Handgrip 0.015

Minimally adjusted model included the covariates age, gender, race, and education Fully adjusted model included the covariates age, gender, race, education, marital status, BMI, handgrip strength, hypertension status, diabetes status, depression status, comorbid score, and serum HDL level.

***

p <0.001,

**

p<0.01,

*

p<0.05,

^

p <0.1 Ref, reference category; CERAD.IR, immediate recall memory test; CERAD.DR, delayed recall memory test; AFT, animal fluency test; DSS, digit symbol substitution test. Effect size is represented by Partial Eta-squared.