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. 2023 Oct 31;41(12):3567–3573. doi: 10.1007/s00345-023-04686-4

Table 2.

Features of the multivariable models to predict long-term postoperative eGFR

Feature Estimate SE P value
RN
Intercept 4.37 4.27 0.31
Age (year) – 0.105 0.0329 0.001
Preoperative eGFR (ml/min/1.73 m2) 0.674 0.0259  < 0.001
RGFR of the operative side (ml/min/1.73 m2) – 0.152 0.0278  < 0.001
RGFR of the healthy side (ml/min/1.73 m2) 0.204 0.0288  < 0.001
Serum cystatin C (mg/L) 0.914 2.30 0.69
Diabetes – 3.57 1.12 0.002
Surgical method
 Open surgery Reference
 Laparoscopic surgery 0.480 0.975 0.62
 Robotic surgery 3.96 1.93 0.04
Time from surgery (month) 0.930 0.137  < 0.001
Preoperative eGFR × time from surgery (month) – 0.00686 0.00101  < 0.001
RGFR of the healthy side × time from surgery (month) 0.00443 0.00107  < 0.001
Serum cystatin C × time from surgery (month) – 0.452 0.0826  < 0.001
Surgical method × time from surgery (month)
 Open surgery Reference
 Laparoscopic surgery 0.105 0.0316 0.001
 Robotic surgery 0.0426 0.0719 0.55
PN
Intercept 15.3 4.91 0.002
Age (year) – 0.103 0.0463 0.03
Preoperative eGFR (ml/min/1.73 m2) 0.864 0.0298  < 0.001
Serum cystatin C (mg/L) – 6.62 2.64 0.01
Surgical method
 Open surgery Reference
 Laparoscopic surgery 2.23 1.63 0.17
 Robotic surgery 2.42 1.64 0.14
Time from surgery (month) 1.78 0.189  < 0.001
Age × time from surgery (month) – 0.00672 0.00177  < 0.001
Preoperative eGFR × time from surgery (month) – 0.0102 0.00128  < 0.001
Serum cystatin C × time from surgery (month) – 0.556 0.0973  < 0.001
Surgical method × time from surgery (month)
 Open surgery Reference
 Laparoscopic surgery 0.183 0.0527  < 0.001
 Robotic surgery 0.163 0.0531 0.002

BMI body mass index; eGFR estimated glomerular filtration rate; PN partial nephrectomy; rGFR glomerular filtration rate measured by radionuclide; RN radical nephrectomy