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. 2023 Nov 10;41(12):3511–3518. doi: 10.1007/s00345-023-04691-7

Table 1.

Characteristics and treatments of patients according to EPIC version administered. Distribution of the EPIC domains’ scores at 12 months after treatment

Patients with EPIC-26 (n = 534) Patients with EPIC-50 (n = 324) p value*
Characteristics
Age at recruitment, years, mean (SD) 68.1 (8.0) 67.9 (8.0) 0.652
Tumoral stage, n (%)
Tx 8 (1.5%) 1 (0.3%) 0.346
T0 1 (0.2%) 1 (0.3%)
T1 250 (46.0%) 162 (50.2%)
T2 184 (33.9%) 102 (31.6%)
T3 97 (17.9%) 57 (17.6%)
T4 3 (0.6%) 0 (0.0%)
PSA, mean (SD) 11.1 (13.8) 9.4 (9.0) 0.049
Gleason score, mean (SD) 7.1 (0.9) 6.8 (1.0) < 0.001
D’Amico tumoral risk, n (%)
Low 94 (17.4%) 102 (31.6%) < 0.001
Intermediate 249 (46.1%) 128 (39.6%)
High 197 (36.5%) 93 (28.8%)
Initial primary treatment
External radiotherapy, n (%) 282 (51.9%) 181 (55.9%) < 0.001
Radical prostatectomy, n (%) 185 (34.1%) 83 (25.6%)
Brachytherapy as monotherapy, n (%) 38 (7.0%) 44 (13.6%)
Active surveillance, n (%) 29 (5.3%) 3 (0.9%)
Focal brachytherapy, n (%) 9 (1.7%) 13 (4.0%)
Distribution of the EPIC scores
Urinary incontinence
Observed range 0–100 0–100
Floor and ceiling effect (%) 0.9%; 54.1% 1.9%; 62.7%
Mean (SD) 77.9 (28.2) 81.5 (27.5)
Cronbach’s alpha 0.90 0.91
Urinary irritative/obstructive
Observed range 0–100 7.1–100
Floor and ceiling effect (%) 0.7%; 42.5% 0.0%; 36.4%
Mean (SD) 80.6 (22.5) 84.5 (17.7)
Cronbach’s alpha 0.67 0.63
Bowel
Observed range 0–100 28.6–100
Floor and ceiling effect (%) 0.4%; 66.1% 0.0%; 61.7%
Mean (SD) 88.1 (21.2) 92.0 (14.1)
Cronbach’s alpha 0.84 0.87
Sexual
Observed range 0–87.5 0–90.4
Floor and ceiling effect (%) 1.8%; 0.0% 0.3%; 0.0%
Mean (SD) 34.8 (27.4) 43.6 (19.9)
Cronbach’s alpha 0.86 0.88
Hormonal
Observed range 0–100 4.6–100
Floor and ceiling effect (%) 1.3%; 38.9% 0.0%; 29.9%
Mean (SD) 74.2 (28.0) 82.2 (19.7)
Cronbach’s alpha 0.78 0.84

*p-values were estimated with Chi-square test or unpaired Student’s t test