Table 2.
Sensitivity to change of the EPIC-50 and the EPIC-26 by treatment group
| Domains and items | Mean (SD) at baseline (T0) | Mean (SD) at 12 months (T1) | Mean difference (SD) (T1 – T0) | Cohen’s Effect Size | ||||
|---|---|---|---|---|---|---|---|---|
| EPIC-26 | EPIC-50 | EPIC-26 | EPIC-50 | EPIC-26 | EPIC-50 | EPIC-26 | EPIC-50 | |
| Radical prostatectomy | n = 95 | n = 79 | n = 95 | n = 79 | n = 95 | n = 79 | n = 95 | n = 79 |
| Urinary incontinence | 93.9 (14.9) | 94.3 (16.0) | 60.3 (32.3) | 59.7 (31.9) | − 33.6 (0.0)* | − 34.6 (34.7)* | 2.25 | 2.16 |
| Urinary irritative/obstructive | 79.9 (19.8) | 89.6 (15.8) | 80.6 (21.5) | 85.5 (20.4) | 0.7 (35.0) | − 4.1 (22.2) | 0.04 | 0.26 |
| Bowel | 96.5 (8.6) | 98.4 (4.3) | 89.4 (21.8) | 95.0 (11.9) | − 7.1 (24.5)* | − 3.4 (12.0)* | 0.83 | 0.78 |
| Sexual | 68.0 (28.4) | 71.6 (17.1) | 40.9 (28.9) | 53.4 (25.1) | − 27.1 (22.7)* | − 18.3 (24.6)* | 0.95 | 1.07 |
| Hormonal | 85.3 (13.1) | 88.9 (11.4) | 81.6 (26.9) | 89.2 (15.8) | − 3.8 (32.7) | 0.3 (14.9) | 0.29 | 0.03 |
| External radiotherapy | n = 115 | n = 170 | n = 115 | n = 170 | n = 115 | n = 170 | n = 115 | n = 170 |
| Urinary incontinence | 86.9 (20.6) | 86.1 (21.5) | 85.0 (23.3) | 87.7 (21.4) | − 1.9 (25.6) | 1.7 (21.2) | 0.09 | 0.08 |
| Urinary irritative/obstructive | 76.1 (19.8) | 85.8 (14.9) | 76.9 (23.7) | 83.2 (17.2) | 0.8 (0.0) | − 2.6 (16.9) | 0.04 | 0.17 |
| Bowel | 93.5 (13.6) | 97.5 (6.2) | 87.0 (21.9) | 90.7 (15.1) | − 6.5 (21.1)* | − 6.7 (15.4)* | 0.48 | 1.09 |
| Sexual | 34.4 (28.9) | 41.9 (19.2) | 21.7 (17.5) | 36.2 (14.2) | − 12.7 (25.9)* | − 5.8 (16.1)* | 0.44 | 0.30 |
| Hormonal | 77.0 (21.8) | 81.1 (15.2) | 61.9 (31.2) | 75.1 (20.8) | − 15.1 (24.1)* | − 6.0 (19.6)* | 0.69 | 0.40 |
*p value was estimated with paired Student’s t test for each subsample and EPIC version