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. 2023 Oct 26;83(17):1581–1593. doi: 10.1007/s40265-023-01950-0
Idiopathic pulmonary fibrosis (IPF) remains a fatal and incurable disease despite the use of approved antifibrotic drugs.
Development of novel antifibrotics drugs has consistently increased over the last decades, but unsolved issues remain about endpoints, duration, and inclusion/exclusion criteria of future clinical trials.
A better knowledge of mechanisms leading to IPF onset and progress is crucial to the development of new compounds.