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. 2023 Dec 2;13:21294. doi: 10.1038/s41598-023-48718-w

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation analysis between clinical parameters that were significantly different between groups (p < 0.05) and gut/fecal microbiome composition. (A) Bar plots showing significant differences in clinical parameters between groups. (B) Correlation matrix showing correlations between clinical parameters and the abundances of microbes. The size and color intensity of the ellipses indicate the strength of positive or negative correlation (blue color, positive correlation; red color, negative correlation). The black asterisk (* < 0.05; ** < 0.01; *** < 0.001) within the ellipses represents the p-value of the statistical test. NCD: Normal chow diet group, HFD: High fat diet group, sHFD: after high fat diet, gastrectomy group.