Table 3.
Cox proportional hazard model for weight change from diagnosis to 1 year and all-cause mortality, N = 4880.
| Large loss (≥10%) | Moderate loss (5–10%) | Stable (within 5%) | Moderate gain (5–10%) | Large gain (≥10%) | |
|---|---|---|---|---|---|
| Breast cancer-specific | Events/N | Events/N | Events/N | Events/N | Events/N |
| 167/4880 | 31/355 | 24/631 | 78/3079 | 26/590 | 8/225 |
| Unadjusted | 3.98 (2.63–6.04) | 1.56 (0.99–2.46) | Ref. | 1.73 (1.11–2.70) | 1.40 (0.68–2.90) |
| Adjusteda | 2.21 (1.42–3.43) | 1.09 (0.68–1.74) | Ref. | 1.80 (1.15–2.82) | 1.15 (0.55–2.41) |
| All-cause mortality | Events/N | Events/N | Events/N | Events/N | Events/N |
| 525/4880 | 95/355 | 79/631 | 273/3079 | 58/590 | 20/225 |
| Unadjusted | 3.64 (2.88–4.59) | 1.50 (1.17–1.93) | Ref. | 1.10 (0.83–1.46) | 1.00 (0.63–1.57) |
| Adjusteda | 2.93 (2.28–3.75) | 1.32 (1.02–1.70) | Ref. | 1.39 (1.04–1.85) | 1.37 (0.87–2.18) |
aAdjusted for Age at diagnosis (continuous), BMI at diagnosis (continuous), Race and ethnicity, Tumor subtype (ER/PR+, HER2−; ER/PR+, HER2+; ER/PR−, HER2+, TNBC), Clinical stage, Chemotherapy (yes/no), and Radiation (yes/no).