Table 2.

Condition optimization for the reaction of p-iodotoluene and benzeneboronic acid-catalyzed using the Ni(II)-β-CD complex.

Entry	Catalyst (mol%Ni)	Base	Solvent	Yielda (%)
1	2.5	K2CO3	THF	5
2	2.5	K2CO3	Toluene	7
3	2.5	K2CO3	CH3CN	11
4	2.5	K2CO3	dioxane	2
5	2.5	K2CO3	DMF	4
6	2.5	K2CO3	EtOH	35
7	2.5	K2CO3	MeOH	21
8	2.5	K2CO3	DMSO	Trace
9	2.5	K2CO3	H2O	96
10	2.5	K2CO3	H2O	41b
11	0.5	K2CO3	H2O	24
12	1	K2CO3	H2O	50
13	1.5	K2CO3	H2O	65
14	2	K2CO3	H2O	79
15	2.5	Cs2CO3	H2O	76
16	2.5	Na2CO3	H2O	79
17	2.5	DABCO	H2O	8
18	2.5	NEt3	H2O	Trace
19	2.5	t‐BuOK	H2O	55

Reaction status: phenylboronic acid, p-iodotoluene, base (with the ratio: 0.75:0.5:0.75), Ni(II)-β-CD complex, and solvent (1 mL) undergo Argon.

^aYield determined by GC.

^bThe reaction was conducted at ambient temperature.

Significant values are in bold.