Table 2.

Biomarker (spikes, HFO, spikes + HFO) and seizure outcome.

	HFO	Spikes	Spikes + HFO
Sensitivity [%] TP/(TP + FN)	57 [18 90]	71 [29 96]	67 [22 96]
Specificity [%] TN/(TN + FP)	100 [75 100]	54 [25 81]	85 [55 98]
PPV [%] TP/(TP + FP)	100 [40 100]	45 [17 77]	67 [22 96]
NPV [%] TN/(TN + FN)	81 [54 96]	78 [40 97]	85 [55 98]
Accuracy [%] (TP + TN)/N	85 [62 97]	60 [36 81]	79 [54 94]

Values in brackets denote the 95% confidence interval. HFO are defined as fast ripples co-occurring with ripples. Abbreviations: FN False Negative, FP False Positive, NPV Negative Predictive Value, PPV Positive Predictive Value, TN True Negative, TP True Positive, N number of patients.