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. 2023 Dec 2;14:7981. doi: 10.1038/s41467-023-43769-z

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Line plots show the ratio of estimated oral antiviral courses needed to number of people per year (expressed as 1 oral antiviral course per n number of individuals; assuming two epidemic waves a year) in simulated countries (color) under different simulated scenarios (i.e., testing rate at 100 or 500 tests/100,000 people/day (shading and linestyle) and distribution modality (left plot panel: test all symptomatic individuals who sought testing at clinics; middle plot panel: test all symptomatic individuals who sought testing as well as distributing clinic-provided self-tests to high-risk asymptomatic household contacts of test-positive individuals; right plot panel: test only high-risk symptomatic individuals who sought testing at clinics). All test-positive eligible high-risk individuals from clinic-provided testing would receive a course of oral antivirals. a 10%, b 50%, and c 90% vaccination coverage assumed for the simulated population.