Table 3:

Post-transplant outcomes and causes of death of lung transplant recipients, 2005-2020.

Variable, n (%)	18-59 years N=13,228	60-69 years N=12,282	≥70 years N=2,448	p-value
ECMO within 72 hours	557 (9.0%)	374 (5.7%)	79 (4.9%)	<0.001
Acute rejection	1,213 (9.2%)	914 (7.4%)	163 (6.7%)	<0.001
Post-operative dialysis	1,006 (7.6%)	738 (6.0%)	127 (5.2%)	<0.001
Hospital LOS (days), median (IQR)	17 (12-29)	16 (11-28)	16 (11-27)	<0.001
Intubation at 72 hours	2,144 (34.5%)	1,814 (27.4%)	353 (21.7%)	<0.001
Treated for rejection within 1 year	3,054 (26.7%)	2,467 (23.6%)	442 (21.7%)	<0.001
Cause of death by 1 year				<0.001
Infection	345 (24.5%)	469 (28.4%)	102 (25.6%)
Hemorrhage	209 (14.8%)	257 (15.6%)	76 (19.1%)
Pulmonary	212 (15.0%)	253 (15.3%)	66 (16.6%)
Cardiovascular	136 (9.6%)	180 (10.9%)	49 (12.3%)
Malignancy	34 (2.4%)	63 (3.8%)	25 (6.3%)
Graft Failure – other	129 (9.1%)	104 (6.3%)	18 (4.5%)
Cerebrovascular	101 (7.2%)	100 (6.1%)	14 (3.5%)
Graft Failure – rejection	74 (5.2%)	61 (3.7%)	11 (2.8%)
Renal Failure	2 (0.1%)	13 (0.8%)	4 (1.0%)
Other	169 (12.0%)	151 (9.1%)	33 (8.3%)
Cause of death by 5 years				<0.001
Infection	785 (18.7%)	1,050 (22.3%)	210 (18.9%)
Pulmonary	907 (21.6%)	857 (18.2%)	210 (18.9%)
Hemorrhage	569 (13.5%)	694 (14.7%)	189 (17.0%)
Malignancy	233 (5.5%)	499 (10.6%)	161 (14.5%)
Cardiovascular	246 (5.8%)	369 (7.8%)	107 (9.6%)
Graft Failure – rejection	745 (17.7%)	588 (12.5%)	97 (8.7%)
Graft Failure – other	210 (5.0%)	171 (3.6%)	34 (3.1%)
Cerebrovascular	151 (3.6%)	156 (3.3%)	26 (2.3%)
Renal Failure	36 (0.9%)	62 (1.3%)	14 (1.3%)
Other	326 (7.7%)	262 (5.6%)	66 (5.9%)

ECMO, extracorporeal membrane oxygenation; LOS, length of stay; IQR, interquartile range.