Table 1.
Data on mice in current and retrospective studies.
| Compound | Conduction of experiment | Number of mice (females) | Age (weeks) | Number of experiments | Procedure and instillation site | ||
|---|---|---|---|---|---|---|---|
| Average | Min | Max | |||||
| F8819 bead-laden agarose beads | Current | 2 (2) | 17.4 | 15.6 | 19.1 | 1 | Bronchoscope, right main bronchus |
| Free F8819 beads | Current | 2 (1) | 21.8 | 12.9 | 30.6 | 2 | Bronchoscope, right main bronchus |
| 25,000 CFU PAM | Retrospective | 17 (8) | 14.2 | 10.1 | 23.1 | 5 | Bronchoscope, trachea |
| 25,000 CFU PAM | Retrospective | 17 (3) | 16.4 | 11.3 | 20.1 | 4 | Transtracheal surgery, trachea |
| 50,000 CFU PAM | Retrospective | 15 (10) | 14.4 | 11.3 | 20.1 | 4 | Bronchoscope, trachea |
| 50,000 CFU PAM | Retrospective | 31 (8) | 11.5 | 6.6 | 27.4 | 10 | Transtracheal surgery, trachea |
| 100,000 CFU PAM | Retrospective | 17 (9) | 11.2 | 8.3 | 14.9 | 4 | Bronchoscope, trachea |
| 100,000 CFU PAM | Retrospective | 15 (10) | 10.8 | 6.9 | 12.9 | 3 | Transtracheal surgery, trachea |