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Clinical trials in MLL-rearranged AML.
| Mutation | Study regimen | Trial identifier |
|---|---|---|
| MLL-rearranged AML | ||
| MLL-rearranged or NPM1mut | DSP-5336 (menin-MLL inhibitor) | NCT04988555 |
| MLL-rearranged or NPM1mut | SNDX-5613 (menin-MLL inhibitor) | NCT04065399 |
| None specified; relapsed or refractory AML | KO-539 (menin-MLL inhibitor) | NCT04067336 |
| MLL-rearranged AML | EPZ-5676 (DOT1L inhibitor) | NCT01684150 |
