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Clinical trials in TP53mut AML.
| Mutation | Study regimen | Trial identifier |
|---|---|---|
| TP53mut AML | ||
| TP53mut AML | Eprenetapopt + azacitidine | NCT03931291 |
| TP53mut AML | Decitabine monotherapy | NCT03063203 |
| TP53mut AML | Magrolimab + azacitidine versus venetoclax + azacitidine or intensive chemotherapy | NCT04778397 |
| None specified; relapsed or refractory AML | Idasanutlin, venetoclax, and cobimetinib | NCT02670044 |
| TP53mut/TP53wt and FLT3mut AML | Siremadlin (TP53/MDM2 inhibitor) + midostaurin | NCT04496999 |
