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. Author manuscript; available in PMC: 2023 Dec 3.
Published in final edited form as: Psychopharmacology (Berl). 2023 Aug 14;240(10):2187–2199. doi: 10.1007/s00213-023-06440-5

Table 5.

Change in the correct choice latency after 2MDHX and CY208 were administered at their optimal or detrimental dose, respectively

Vehicle 2MDHX CY208
Optimal Detrimental Optimal Detrimental
Time to make correct choices (S) Mean ± SD 7.9 ± 4.5 7.3 ± 8.8 15.6 ± 13.3 8.5 ± 7.8 6.3 ± 7.6
Vehicle x 0.839 0.130 0.823 0.560
2MDHX Optimal 0.839 x 0.136 0.736 0.798
Detrimental 0.130 0.136 x 0.185 0.089
CY208 Optimal 0.823 0.736 0.185 x 0.515
Detrimental 0.560 0.798 0.089 0.515 x
CV (%) 103 ± 28 128 ± 53 86 ± 54 115 ± 56 106 ± 58
Vehicle x 0.228 0.4 0.545 0.875
2MDHX Optimal 0.228 x 0.115 0.596 0.395
Detrimental 0.4 0.115 x 0.258 0.43
CY208 Optimal 0.545 0.596 0.258 x 0.731
Detrimental 0.875 0.395 0.43 0.731 x

CV indicates trial-to-trial variation. p values of pairwise comparisons are reported on the rows under the mean ± SD or CV. Least significant difference was used for multiple comparisons adjustment. Note 2MDHX caused slightly longer correct choice latency compared to CY208 when they were administered at their detrimental doses respectively. x, not tested or not applicable