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图1. 48例难治复发弥漫大B细胞淋巴瘤患者治疗前的血清样本的循环肿瘤DNA(ctDNA)突变景观图 A 6种主要突变数目柱状图; B 3种突变类型柱状图,SNP:点突变;DEL:缺失突变;INS:插入突变; C 6种SNV突变频谱; D 每个样本ctDNA突变数目柱状图; E 所有样本6种主要突变数目箱型图,从左往右分别代表错义突变、移码缺失、非移码缺失、剪切突变、移码插入、非移码插入; F 突变频率前10基因的突变频率; G 突变频率最高的15个基因的变异等位基因频率分布.