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. 2023 Mar 1;66(9):1971–1978. doi: 10.1007/s10840-023-01512-0

Table 2.

Baseline characteristics

Group I with CIED (%) Group II without CIED (%) p value
Total number of patients 31 243
Gender male 20 (64.5) 152 (62.6) 0.831
Age in years 73.7 ± 5.4 69.3 ± 8.2  < 0.001
AF-type
  Paroxysmal AF 16 (51.6) 118 (48.6) 0.736
  Persistent 5 (16.1) 54 (22.2)
  Permanent 10 (32.3) 71 (29.2)
CHA2DS2-VASc (mean ± SD) 4.3 ± 1.5 3.8 ± 1.5 0.104
  Low–intermediate risk (0–3) 9 (29.0) 111 (45.7) 0.079
  High risk (> 3) 22 (71.0) 132 (54.3)
HAS-BLED 3.3 ± 1.0 2.8 ± 1.0 0.021
  Low–intermediate risk (0–3) 17 (54.8) 188 (77.4) 0.007
  High risk (> 3) 14 (45.2) 55 (22.6)
History of ischemic stroke 7 (22.6) 80 (32.9) 0.244
History of major bleeding: 26 (83.9) 134 (55.1) 0.002
  Intracranial haemorrhage 15 (48.4) 75 (30.9) 0.050
  Other 13 (41.9) 66 (27.2) 0.087
APT or (N)OAC use prior to LAAO *:
  None 5 (16.1) 42 (17.3) 0.872
  Aspirin 13 (44.8) 46 (20.5) 0.004
  Clopidogrel 3 (9.7) 28 (11.5) 1.000
  VKA 7 (22.6) 98 (40.3) 0.056
  NOAC 4 (12.9) 41 (16.9) 0.574
  Persantin 2 (6.6) 4 (1.6) 0.139

AF, atrial fibrillation; CIED, cardiac implantable electronic device; (N)OAC, (novel) oral anticoagulation; SD, standard deviation; VKA, vitamin K antagonist

*Medication use scored at day directly before LAAO