Table 3.
The effects of compounds (1a-1n) on the viability of Ovarian cancer cell lines ID8 (n = 3). IC50 values of synthesized compounds and reference drug cisplatin.
| Compound | IC50 (μM) | |
|---|---|---|
| 1. | 1a | 23.86 ± 0.61 |
| 2. | 1b | 14.8 ± 0.70 |
| 3. | 1c | 15.68 ± 0.64 |
| 4. | 1d | 25.27 ± 0.82 |
| 5. | 1e | 26.45 ± 0.72 |
| 6. | 1f | 158.4 ± 0.66 |
| 7. | 1g | 146.1 ± 0.56 |
| 8. | 1h | 9.407 ± 0.73 |
| 9. | 1i | 11.2 ± 0.22 |
| 10. | 1j | 21.49 ± 0.11 |
| 11. | 1k | 64.17 ± 0.88 |
| 12. | 1l | 15.64 ± 0.77 |
| 13. | 1m | 32.39 ± 0.67 |
| 14. | 1n | 47.92 ± 0.75 |
| 15. | Cisplatin | 8.502 ± 0.23 |