Table 2.

Results of heterogeneity and horizontal pleiotropy tests.

Diseases	Heterogeneity test		Horizontal pleiotropy test
	MR-Egger regression	IVW model	MR-Egger intercept	MR-PRESSO test
Schizophrenia	<0.001	<0.001	0.570	0.025
Depression	0.067	0.080	0.783	0.140
Anxiety disorder	0.247	0.233	0.252	0.116
Panic disorder	0.055	0.064	0.605	0.096
Insomnia	0.493	0.532	0.730	0.621
Obsessive compulsive disorder	0.767	0.800	0.878	0.586
Bipolar disorder	<0.001	<0.001	0.968	0.388

Sensitivity analyses consist of heterogeneity and horizontal pleiotropy tests. A p-value less than 0.05 was considered significant in both tests.