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. 2023 Nov 20;10:1256997. doi: 10.3389/fvets.2023.1256997

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Copyright © 2023 Crosby, Karisch, Hiott, Pinnell, Pittman, Frye, Jackson, Loy, Epperson, Blanton, Capik, Morley and Woolums.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heatmaps of in vitro susceptibility of isolated MH. (A) Arrival isolates, (B) WK3 isolates, (C) WK10 isolates, and (D) all isolates combined. TxGroup, treatment group; AM Before, treated with antimicrobial before isolation; MALDI, MALDI biomarker genotype; F19, Fall 2019; F20, Fall 2020; S21, Spring 2021; F21, Fall 2021; META, tulathromycin metaphylaxis; NO META, no tulathromycin metaphylaxis; MLS, macrolide-lincosamide-streptogrammin; ICE, integrative conjugative element; Y, Yes; N, No; WK3, week 3; WK10, week 10. Key: 0 = Not interpretable, 1 = susceptible, 2 = not susceptible.