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. 2023 Oct 30;17(6):1238–1254. doi: 10.4162/nrp.2023.17.6.1238

Table 2. Differences in changes in anthropometrics and metabolic biomarkers between the App group and the Paper group.

Characteristics (mean ± SD) App group (n = 30) Paper group (n = 27) P-value3)
Baseline 12-week Change (%)1) P-value2) Baseline 12-week Change (%)1) P-value2)
Anthropometrics
Body weight (kg) 81.4 ± 12.5 82.1 ± 13.5 0.7 ± 3.0 0.14 78.5 ± 9.6 77.9 ± 10.4 −0.9 ± 3.2 0.18 0.11
BMI (kg/m2) 28.2 ± 3.1 28.4 ± 3.3 0.7 ± 3.0 0.71 27.7 ± 2.2 27.4 ± 2.4 −0.9 ± 3.2 0.16 0.11
Body fat (kg) 26.2 ± 8.3 27.3 ± 9.0 4.2 ± 10.9 0.03 26.5 ± 6.9 26.0 ± 6.8 −1.6 ± 7.2 0.24 0.03
Lean body mass (kg) 55.2 ± 10.5 54.7 ± 10.3 −0.7 ± 4.0 0.25 52.0 ± 9.1 51.9 ± 9.6 −0.5 ± 2.6 0.52 0.82
Skeletal muscle mass (kg) 30. 9 ± 6.4 30.7 ± 6.3 −0.6 ± 4.3 0.34 29.1 ± 5.6 29.0 ± 5.9 −0.4 ± 2.7 0.74 0.83
Waist circumference (cm) 94.5 ± 8.5 93.6 ± 10.1 −1.0 ± 4.3 0.26 93.0 ± 6.9 91.3 ± 6.9 −1.8 ± 4.4 0.04 0.59
Body fat percent (%) 32.2 ± 8.4 33.1 ± 8.3 3.4 ± 9.3 0.06 33.8 ± 7.8 33.5 ± 7.8 −0.8 ± 4.9 0.35 0.06
Metabolic biomarkers
Fasting glucose (mg/dL) 91.7 ± 6.6 92.7 ± 6.2 1.4 ± 7.0 0.39 93.6 ± 8.8 93.1 ± 7.5 −0.2 ± 5.1 0.64 0.34
Total cholesterol (mg/dL) 168.2 ± 30.8 179.8 ± 32.3 9.6 ± 29.4 0.04 187.6 ± 24.0 187.6 ± 27.2 0.4 ± 11.7 0.74 0.06
Triglyceride (mg/dL) 92.1 ± 33.2 118.8 ± 79.0 31.0 ± 59.6 0.01 99.1 ± 36.5 108.0 ± 42.8 14.3 ± 42.2 0.28 0.23
HDL-cholesterol (mg/dL) 52.6 ± 9.1 53.2 ± 7.5 2.2 ± 11.9 0.65 52.6 ± 8.5 55.3 ± 9.2 5.8 ± 12.2 0.03 0.26
LDL-cholesterol (mg/dL) 97.0 ± 26.8 102.9 ± 26.8 12.5 ± 45.3 0.11 115.2 ± 22.7 110.7 ± 26.8 −3.1 ± 20.6 0.29 0.02
Insulin (μU/mL) 11.0 ± 6.0 12.5 ± 8.0 19.7 ± 43.8 0.20 11.7 ± 8.5 11.2 ± 7.4 11.6 ± 61.8 0.84 0.25
hsCRP (mg/L) 1.1 ± 0.9 1.1 ± 0.8 34.7 ± 135.6 0.86 1.4 ± 1.7 1.2 ± 1.6 −8.4 ± 60.8 0.01 0.27

BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; hsCRP, high sensitivity C-reactive protein; App, mobile application; Paper, paper-based diary.

1)Change from baseline to 12 weeks is defined as relative change: Formula = [(Follow-Up Measurement – Baseline Measurement)/Baseline Measurement] × 100.

2)P-value was calculated using paired t-test and Wilcoxon signed-rank test, and represented the difference from pre- to post-intervention within the group.

3)P-value was calculated using independent t-test and Wilcoxon rank sum test, and represented the difference of the relative change between the App group and the Paper group.