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Transcriptomic analysis revealed upregulation of (A) CD83, (B) CRTAM, (C) CD8B, and (D) CXCL9 only in samples treated with combinatorial therapy. Transcriptomic analysis revealed upregulation of chemokines (E) CXCL3, (F) CXCL10, (G) CXCL11, and (H) TAP1 in samples treated with only AdV5/3-D24-ICOSL-CD40L, only anti-PD-1, or both AdV5/3-D24-ICOSL-CD40L + anti-PD-1 regimen, *p ≤ 0.1, **p ≤ 0.05, ***p<0.01; ns, not significant.
