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. 2023 Oct 27;299(12):105389. doi: 10.1016/j.jbc.2023.105389

Figure 2.

Figure 2

SweetTrac2 recognizes 14 compounds transported by AtSWEET1.A, cartoon describing the yeast cell that was used to collect the steady-state response of SweetTrac2. AtSWEET1 (orange) is the solo hexose transporter on the plasma membrane, and SweetTrac2 (green) is expressed on the vacuolar membrane of EBY4000 cells. B–O, SweetTrac2′s steady-state response to sugar and sugar analogs transported by AtSWEET1. The carbons are numbered for D-glucose. The sugar concentrations listed correspond to the levels in the extracellular media. Blue solid lines represent uniporter model fit as described in Park et al. 2022 (16), and the shaded areas represent 95% confidence intervals. Equilibrium exchange constants are reported as estimated ± 95% confidence intervals (n = 5). All chemical structures are depicted in their most probable conformation in aqueous solution. SWEET, Sugars Will Eventually be Exported Transporter.