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A9E and G9E BOB reactivity in validation sample set. (a and b) Percent A9E and G9E blockade grouped by flavivirus-immune status. See Methods for details for flavivirus immune status determination. (c and d) ROC curves depicting results from validation samples (AUC = 0.992 for A9E BOB and AUC = 1.0 for G9E BOB). (e and f) Sensitivity and specificity plotted according to %BOB (x-axis) to visualize cut-off determination.
