Table 2.
Application of BOB assay to Colombia AIP samples.
| ZIKV status | DENV screen status | % A9E BOB positive | % G9EBOB positive | % A9E AND G9E BOB positive | % A9E OR G9E BOB positive |
|---|---|---|---|---|---|
| ZIKV Negative | Naïve | 0% (0/13) | 7.7% (1/13) | 0% (0/13) | 7.7% (1/13) |
| Monotypic DENV | 12% (3/25) | 32% (8/25) | 8% (2/25) | 36% (9/25) | |
| Multitypic DENV | 22% (7/32) | 40% (13/32) | 13% (4/32) | 50% (16/33) | |
| Total | 14% (10/70) | 31% (22/70) | 7.5% (6/70) | 37% (26/70) | |
| ZIKV Positive | Naïve | 100% (2/2) | 100% (2/2) | 100% (2/2) | 100% (2/2) |
| Monotypic DENV | 75% (3/4) | 75% (3/4) | 75% (3/4) | 75% (3/4) | |
| Multitypic DENV | 56% (9/16) | 81% (13/16) | 56% (9/16) | 81% (13/16) | |
| Total | 71% (14/22) | 82% (18/22) | 64% (14/22) | 82% (18/22) |
% A9E and G9E BOB ELISA positivity rate by ZIKV and DENV classification based on thresholds set by previous ROC analysis.