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. 2023 Dec 4;13(50):35251–35291. doi: 10.1039/d3ra07391b

Highlights the characteristics and applications of nanocomposite hydrogels based on the type of their nanoparticles: carbon-based, polymeric-based, inorganic-based, and metallic-based hydrogels.

Category Nanoparticle types Characteristics Applications
Carbon-based nanocomposite hydrogels Carbon nanotubes (CNTs), graphene, graphene oxide Exceptional mechanical, electrical, and thermal properties Tissue engineering scaffolds
Improved strength, conductivity, and thermal stability Flexible electronics sensors
Polymeric-based nanocomposite hydrogels Nanofibers, micelles, dendrimers Structural support, enhanced drug encapsulation, regulated release kinetics Drug delivery
Wound healing
Tissue regeneration
Inorganic-based nanocomposite hydrogels Silica nanoparticles, hydroxyapatite, metal oxides Modulated mechanical strength, improved bioactivity, controlled ion release Bone tissue engineering
Dental materials
Controlled drug delivery
Antimicrobial agent
Metallic-based nanocomposite hydrogels Gold nanoparticles, silver nanoparticles Distinct optical, antimicrobial, photothermal, and catalytic properties Wound dressings
Enhanced antimicrobial activity, localized drug release Cancer therapy
Antibacterial applications