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. 2023 Nov 8;4(11):101277. doi: 10.1016/j.xcrm.2023.101277

Figure 2.

Figure 2

Features of the successful organoid culture tissues

(A) Clinical features of successful organoid culture tissues. Clinical features are indicated with a color code. ∗p < 0.05.

(B) Volcano plots showing differentially expressed genes of successful organoid culture tissues and failed organoid culture tissues. Wilcoxon rank-sum test. Benjamini-Hochberg (BH) adjusted p value < 0.05.

(C) Pathways enriched in successful and failed organoid culture tissues. Permutation test. BH adjusted p value < 0.05. NES, normalized enrichment scores.

(D) Representative IHC images of formalin-fixed paraffin-embedded BTC samples belonging to the two groups and stained with the indicated specific antibodies. Quantification of staining intensities for the indicated markers was performed in 80 BTC tissue samples. Scale bar, 50 μm.