Table 2.
The frequency of genotypes and alleles of COMT rs4680 in combat sports athletes and controls.
| Combat sports athletes | Controls | Co-dominant model χ2 (p value) |
OR (95% Confidence, p value ) |
Additive model Cochran-Armitage trend test Z (p value) |
|
|---|---|---|---|---|---|
| COMT rs4680 | |||||
| n = 258 | n = 278 | ||||
| G/G | 63 (24.42%) | 60 (21.58%) | 8.621 (0.0134)* | −2.307 (0.0211) | |
| G/A | 138 (53.49%) | 125 (44.96%) | 1.05 (0.68–1.61, p = 0.4093) | ||
| A/A | 57 (22.09%) | 93 (33.45%) | 0.58 (0.36–0.94, p = 0.0145)* | ||
| G | 264 (51.16%) | 245 (44.06%) | 5.410 (0.0201) | ||
| A | 252 (48.84%) | 311 (55.94%) | |||
p: statistical significance, χ2: Chi2 test result, n: number of subjects, * significant statistical difference, OR: Odds Ratio, G/G and A/A: genotypes (homozygotes), G/A: genotype (heterozygote), G and A: alleles