Table 2. . CYP2C19 haplotype frequencies across six continental African populations in this study.
| Allele frequencies (%) | |||||||
|---|---|---|---|---|---|---|---|
| Haplotype | CPIC function | SEB | YRI | MSL | LWK | GWD | ESN |
| *1 | Normal function | 52 | 49 | 53 | 55 | 52 | 48 |
| *2 | No function | 19 | 17 | 17 | 18 | 13 | 20 |
| *3 | No function | 0 | 0 | 0 | 1 | 0 | 0 |
| *9 | Decreased function | 3 | 0 | 2 | 1 | 1 | 1 |
| *10 | Decreased function | 0 | 0 | 1 | 0 | 0 | 0 |
| *12 | Uncertain function | 1 | 0 | 0 | 0 | 0 | 0 |
| *13 | Normal function | 1 | 2 | 1 | 4 | 3 | 0 |
| *15 | Normal function | 5 | 0 | 0 | 1 | 3 | 1 |
| *17 | Increased function | 17 | 24 | 24 | 18 | 24 | 26 |
| *30 | Uncertain function | 0 | 0 | 0 | 0 | 0 | 1 |
| *35 | No function | 3 | 6 | 2 | 2 | 3 | 2 |
| *38 | Normal function | 1 | 0 | 1 | 0 | 0 | 1 |
| *39 | Uncertain function | 0 | 2 | 0 | 0 | 1 | 2 |
CPIC: Clinical Pharmacogenomics Implementation Consortium; ESN: Esan in Nigeria; GWD: Mandinka in western divisions of The Gambia; LWK: Luhya in Webuye, Kenya; MSL: Mende in Sierra Leone; SEB: Southeastern Bantu; YRI: Yoruba in Ibadan.