Mechanically assisted trials of rutin acylation in 10 : 1 acetonitrile : DMSO with CalB.
| Exp. no. | Dehydrating agent | Fatty acid | Agitation and conditions | Conversion% |
|---|---|---|---|---|
| 20 | MS4Å (100 g dm−3) | Octanoic acid (100 eq.) | Magnetic stirrer bar, 55 °C, 24 h | Nila |
| 21 | SiO2 (32.9 g dm−3) | Octanoic acid (100 eq.) | Ultrasonic, 45–60 °C, 2 h | Nila |
| 22 | SiO2 (32.9 g dm−3) | Octanoic acid (100 eq.) | Shaking waterbath, 55 °C, 24 h | 28% |
| 23 | SiO2 (32.9 g dm−3) | Octanoic acid (100 eq.) | Shaking waterbath, 55 °C, 72 h | 28% |
| 24 | SiO2 (32.9 g dm−3) | Octanoic acid (10 eq.) | Shaking waterbath, 55 °C, 72 h | 9% |
| 25 | SiO2 (32.9 g dm−3) | Palmitic acid (50 eq.) | Shaking waterbath, 55 °C, 72 h | Traces |
| 26 | SiO2 (32.9 g dm−3) | Octanoic acid (100 eq.) | Rotating wheel, r.t., 48 h | 21% |
a
Resin (both Immobead 150 and acrylic resin) breakage caused by too much agitation.