Table 3.

Pharyngeal acidic reflux does not correlate with reflux symptom index (RSI) or reflux finding score (RFS) in patients with LPR (all patients)

Pharyngeal reflux	All patients (N = 27)
	Numbera and durationb of reflux episodes	Correlation with RSI r#	Correlation with RFS r#
pH < 4.0
Number	0[0–1]	− 0.29	− 0.07
Duration	6 ± 3 s	− 0.08	− 0.15
pH < 4.5
Number	1[0–1]	− 0.27	+ 0.15
Duration	16 ± 6 s	− 0.10	− 0.04
pH < 5.0
Number	1[0–2]	− 0.23	+ 0.07
Duration	32 ± 12 s	− 0.15	+ 0.00
pH < 5.5
Number	4[1.5–6.5]	− 0.04	− 0.03
Duration	63 ± 18 s	− 0.14	− 0.06
pH < 6.0
Number	14[8–20.5]	+ 0.29	+ 0.23
Duration	279 ± 49 s	+ 0.04	+ 0.11
Upright
pH < 6.0
Number	13[7–18.5]	+ 0.29	+ 0.22
Supine
pH < 6.0
Number	3[1–4.5]	− 0.03	+ 0.00
Impedance refluxc [7]
Number	1[0.5–3]	− 0.29	− 0.07
Impedance refluxd [25]
Number	0[0–1]	− 0.29	− 0.16

^aNumber of reflux episodes per 24 h for indicated pH values expressed as median[IQR]

^bDuration of pharyngeal acid exposure per 24 h for indicated pH values expressed as mean ± SEM

^cLPR was defined according to Zerbib et al. [7]. No correlation was found even when upright, and supine LPR was analyzed separately (not shown)

^dLPR was defined according to Kawamura et al. [23]. No correlation was found even when upright, and supine LPR was analyzed separately (not shown)

^#Pearson correlation coefficient r > 0.32 is required for significant positive directional correlation (P < 0.05)