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. 2023 Dec 4;23:2405. doi: 10.1186/s12889-023-17236-9

Table 3.

Associations of RWG and BMI trajectories in the first two years of life and early AR

Physical growth indicators Sample size (n) Early AR[RR (95%CI)]
Model 1 Model 2
RWG (vs. NRWG)
Birth-12 months
RWG 1162 1.22(1.08,1.38)** 1.21(1.07,1.37)**
Non-RWG 1406 1.00 1.00
Birth-18 months
RWG 971 1.48(1.31,1.67)** 1.48(1.30,1.67)**
Non-RWG 1598 1.00 1.00
Birth-24 months
RWG 930 1.60(1.41,1.82)** 1.59(1.40,1.81)**
Non-RWG 1524 1.00 1.00
BMI trajectories
Birth-24 months
Low BMI trajectory 395 1.22(1.01,1.46)* 1.27(1.06,1.53)**
Rising BMI trajectory 225 1.52(1.24,1.87)** 1.50(1.22,1.84)**
Medium BMI trajectory 951 1.00 1.00
High BMI trajectory 866 0.98(0.84,1.14) 0.96(0.82,1.11)
Very high BMI trajectory 268 1.17(0.95,1.45) 1.04(0.84,1.28)
Head circumference trajectories
Birth-24 months
Low head circumference trajectory 728 1.09(0.93,1.28) 1.12(0.97,1.28)
Medium head circumference trajectory 1425 1.00 1.00
High head circumference trajectory 552 1.18(0.99,1.41) 0.93(0.79,1.09)

Abbreviations: BMI, body mass index; RWG, rapid weight gain; NRWG, no rapid weight gain; AR, adiposity rebound

Model 1: Crude model

Model 2: Adjusted for maternal age, family monthly income per capita, maternal education level, paternal education level, maternal pre-pregnancy BMI, paternal BMI, parity, maternal metabolic dysfunctions during pregnancy, alcohol use during pregnancy, tobacco use during pregnancy, iron supplementation during pregnancy, folic acid supplementation during pregnancy, and children’s sex

*: P < 0.05; **: P < 0.01