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FIG. 4.

FIG. 4.

Kinetic analysis of IFN-α/β mRNA induction by real-time PCR. Isolated, skin-derived DC were incubated in the presence of infectious FMDV, either live or UV-inactivated strain A24, an attenuated derivative of the A12 strain lacking the leader protease (LLA12), or a medium control (MC). The analysis was internally controlled by measuring 18S rRNA levels. The cytokine mRNA levels for each treatment are expressed as log10 mRNA levels. Data are means ± standard errors (SE) of two experiments.